Risk Assessment

• Pathogenicity of material – disease incidence and severity

• Routes of Transmission – parenteral, airborne or ingestion

• Agent Stability – ease of decontamination

• Infectious Dose – LD50

• Concentration – infectious organisms/vol. & working volume

• Origin of material - Wild Type, exotic, primary cells

• Availability of effective prophylaxis – Hep. B vaccine

• Medical surveillance – exposure management

• Skill level of staff

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